Representation of the Signal Transduction with Aberrance Using Ipi Calculus
نویسندگان
چکیده
The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interference pi calculus, is introduced to describe the signal transduction with aberrance. The calculus is obtained by adding two aberrant actions into the pi calculus and a tag system to check existing aberrance. A model of the signal transduction, RTK-MAPK, with the aberrant Ras is highlighted to illustrate the expressive power of the Ipi calculus.
منابع مشابه
Typing Aberrance in Signal Transduction
We have developed a calculus, called Ipi, for describing the aberrance in biological models. Our approach extends the traditional pi calculus to handle aberrant process in the signal transduction. In this paper we propose a typing system that replaces the tag system of Ipi calculus. It is shown that the typing system is equal to the tag system in terms of the expressive power.
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